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Examples of European classification of precancerous lesions [9]. A: AIN grade I: Cellular and nuclear abnormalities are confined to the lower 1/3 of the epithelium; B: AIN grade II: Cellular and nuclear abnormalities affect 2/3 of the epithelium; C: AIN grade III: Cellular and nuclear anomalies affect the full thickness of the epithelium. AIN: Anal intraepithelial neoplasia.
