Table 1. Study characteristics of PE cases and controls in the analysis of VEGF polymorphisms.
| Author [Ref.] | Year | Country | Ethnicity | Sources of controls | Number | Polymorphism(s) | Genotyping method | Association findings | |
|---|---|---|---|---|---|---|---|---|---|
| Case | CTR | ||||||||
| Lu [10] | 2017 | China | Xanthoderm | HB | 156 | 286 | rs3025039 | Snapshot | NS |
| Amosco [11] | 2016 | Philippines | Xanthoderm | HB | 165 | 191 | rs3025039 rs2010963 |
MassARRAY system | Supportive NS |
| Salimi [12] | 2015 | Iran | Caucasian | HB | 192 | 186 | rs2010963 | PCR-RFLP | Supportive |
| Silva [13] | 2015 | Brazil | Caucasian | HB | 79 | 210 | rs2010963 | PCR-RFLP | NS |
| Zhang Honghui [14] | 2014 | China | Xanthoderm | HB | 58 | 70 | rs3025039 rs2010963 |
Sequencing | Supportive NS |
| Procopciuc [15] | 2014 | Romania | Caucasian | HB | 70 | 94 | rs3025039 | PCR-RFLP | Supportive |
| Chedraui [16] | 2013 | Ecuador | Indo-European hybrid | HB | 31 | 31 | rs3025039 rs2010963 |
Sequencing | NS |
| Andraweere [17] | 2013 | Australia | Caucasian | HB | 174 | 168 | rs3025039 | MassARRAY system | NS |
| Atis [18] | 2012 | Turkey | Caucasian | HB | 34 | 58 | rs3025039 | MassARRAY system | NS |
| Chen Baoli [19] | 2011 | China | Xanthoderm | HB | 84 | 71 | rs3025039 | PCR-RFLP | Supportive |
| He Yun [20] | 2011 | China | Xanthoderm | HB | 61 | 43 | rs3025039 rs2010963 |
Sequencing | Supportive |
| Garza-Veloz [21] | 2011 | Mexico | Indo-European hybrid | HB | 86 | 78 | rs2010963 | PCR-RFLP | NS |
| Cunha [22] | 2010 | Brazil | Caucasian | HB | 52 | 28 | rs3025039 | PCR-RFLP | NS |
| Liu Shifang [23] | 2010 | China | Xanthoderm | HB | 84 | 71 | rs3025039 | PCR-RFLP | Supportive |
| Huang Yuliang [24] | 2009 | China | Xanthoderm | HB | 128 | 231 | rs3025039 | PCR-RFLP | Supportive |
| Sandrim [25] | 2008 | Brazil | Caucasian | HB | 94 | 108 | rs2010963 | TaqMan-assays | NS |
| Nagy [26] | 2008 | Hungary | Caucasian | HB | 71 | 93 | rs2010963 | real-time PCR | NS |
| Shim [27] | 2007 | Korea | Xanthoderm | HB | 110 | 209 | rs3025039 | PCR-RFLP | Supportive |
| Kim [28] | 2007 | Korea | Xanthoderm | HB | 223 | 237 | rs3025039 rs2010963 |
Snapshot | NS |
| Banyasz [29] | 2006 | Hungary | Caucasian | HB | 84 | 96 | rs2010963 | PCR-RFLP | Supportive |
| Papazoglou [30] | 2004 | Sweden | Caucasian | HB | 42 | 73 | rs3025039 rs2010963 |
PCR-RFLP | Supportive NS |
Abbreviations: CTR, control; HB: hospital-based study; NS: non-significant.