Table 1. Comparison of CIBERSORT immune cell fractions between normal tissues and tumor tissues in GC.
Immune cell type | CIBERSORT fraction in % of all infiltrating immune cells | |||
---|---|---|---|---|
P-value | Normal means | Tumor means | logFC | |
Naive B cells | 0.237 | 0.033 | 0.055 | 0.742 |
Memory B cells | 0.634 | 0.027 | 0.018 | −0.590 |
Plasma cells | <0.001 | 0.297 | 0.052 | −2.523 |
CD8 T cells | 0.562 | 0.146 | 0.172 | 0.230 |
Naive CD4 T cells | NA | NA | NA | NA |
Resting CD4 memory T cells | 0.047 | 0.185 | 0.114 | −0.700 |
Activated CD4 memory T cells | 0.033 | 0.009 | 0.053 | 2.484 |
Follicular helper T cells | 0.100 | 0.021 | 0.036 | 0.814 |
Tregs | 0.019 | 0.047 | 0.075 | 0.674 |
γδ T cells | 1 | 0.003 | 0.002 | −0.153 |
Resting NK cells | 0.089 | 0.005 | 0.020 | 1.896 |
Activated NK cells | 0.426 | 0.016 | 0.012 | −0.393 |
Monocytes | 0.205 | 0.014 | 0.008 | −0.769 |
M0 macrophages | <0.001 | 0.012 | 0.133 | 3.472 |
M1 macrophages | 0.001 | 0.022 | 0.074 | 1.769 |
M2 macrophages | 0.116 | 0.065 | 0.085 | 0.387 |
Resting dendritic cells | 1 | 0.019 | 0.022 | 0.200 |
Activated dendritic cells | 0.528 | 0.008 | 0.014 | 0.793 |
Resting mast cells | 0.509 | 0.040 | 0.026 | −0.596 |
Activated mast cells | 0.390 | 0.013 | 0.017 | 0.327 |
Eosinophils | 0.591 | 0.005 | 0.004 | −0.308 |
NA: not available.