Table 2.
Summary of Transplanted Mice
| Graft injection (mouse ID) | Weight, % | Appearance at death | Cyst | Injection point | Epithelial damage | Blood accumulation in graft |
|---|---|---|---|---|---|---|
| HIO PBS (6471) | 101 | Ok | 1 | Not visible | None | Minor: in villi and mesenchyme |
| HIO PBS (6472) | 99 | Ok | 1.5 | Visible | None | Minor: in villi and mesenchyme |
| HIO PBS (6473) | 101 | Ok | 2 | Not visible | None | Minor: in villi and mesenchyme |
| HIO + ENS PBS (6603) | 105 | Ok | 2 | Visible | None | Moderate: in villi and mesenchyme |
| HIO + ENS PBS (6604) | 101 | Ok | 2 | Not visible | None | Minor: in mesenchyme |
| HIO + ENS PBS (6605) | 102 | Ok | Uncertain | – | No engraftment | |
| HIO 10 ng Stx2a (6464) | 97 | Huddled in corner | 1 | Not visible | None | Minor: in villi Moderate: in mesenchyme |
| HIO 10 ng Stx2a (6465) | 96 | Ok | 3 | Not visible | None | Minor: in villi and mesenchyme |
| HIO 10 ng Stx2a (6474) | 82 | Slow movement | 3 | Visible | Loss of epithelium in injected cyst | Minor: in villi Moderate: in mesenchyme |
| HIO + ENS 10 ng Stx2a (6597) | 81 | Sick, hunched, heavy breathing, lethargic, loss of body hair | 1 | Not visible | Significant epithelial loss in cyst | Moderate: in villi Significant: in mesenchyme |
| HIO + ENS 10 ng Stx2a (6598) | 88 | Ok | 1 | Not visible | Significant epithelial loss in cyst | Significant: in mesenchyme |
| HIO + ENS 10 ng Stx2a (6599) | 84 | Sick, hunched, heavy breathing, lethargic, lost body hair | 1 | visible | Minor epithelial loss in cyst | Moderate: in villi Minor: in mesenchyme |