Table 3.
Genotypes frequencies.
| Gene | Reference SNP | Allele (Wild/Mutated) | Frequency W/W | Frequency W/M | Frequency M/M |
|---|---|---|---|---|---|
| ADORA2A | rs5751876 | C/T | 33.3 | 59.3 | 7.4 |
| (35.9) | (45.6) | (18.5) | |||
| [37.4] | [47.1] | [15.5] | |||
| TNF-α | rs1800629 | G/A | 75.5 | 18.9 | 5.6 |
| (74.1) | (24.6) | (1.3) | |||
| [74.4] | [24.5] | [1.2] | |||
| ADA | rs73598374 | C/T | 87.2 | 12.8 | 0 |
| (89.2) | (10.4) | (0.4) | |||
| [88.1] | [11.5] | [0.4] | |||
| COMT | rs4680 | G/A | 29.2 | 45.8 | 25 |
| (30.4) | (49) | (20.6) | |||
| [26.4] | [47.1] | [26.4] | |||
| PER3 | rs228697 | C/G | 89.8 | 10.2 | 0 |
| (82.7) | (16.4) | (0.9) | |||
| [81.7] | [17.3] | [1] |
Data in percent (%) of the n = 42 subjects, % of the 1023 European volunteers in parentheses and % of the 1000 Genomes project in brackets. W is the wild allele, M is the mutated allele and W/M correspond to heterozygous subject.