Table 1.
Examples of immune signaling factors and hormones that are increased in psychiatric patients.
| Biomarker | Disorder | References |
|---|---|---|
| IL-1β | BD, SCZ | [70, 71, 163, 165, 170, 175, 177, 214, 215] |
| IL-4, IL-5, IL-13 | ASD | [181] |
| IL-6 | MDD, BD, SCZ | [49, 51, 70, 71, 163, 172, 173, 174, 176, 177, 179] |
| IL-12 | SCZ | [177] |
| TNF-α | MDD, BD, SCZ | [49, 51, 69, 70, 71, 163, 172, 174, 177] |
| sTNFR1 | BD | [69, 71] |
| sTNFR2 | BD, ASD | [69, 180] |
| TGF-β | SCZ | [177] |
| CRP | MDD, BD | [49, 69, 70, 71, 173, 192] |
| IFN-α/β pathway | MDD | [171] |
| cortisol | MDD, BD, SCZ | [30, 51, 179, 195, 196, 197, 198, 199, 200] |
| insulin | SCZ | [30, 199, 200, 207, 213] |