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. 2020 May 20;3(5):e205252. doi: 10.1001/jamanetworkopen.2020.5252

Table 5. Potential Contraindications by Type of Prescription Provider.

Variable No. (%) P value
Clinician (n = 266) Pharmacist (n = 144) Total (n = 410)
Potential contraindication with estrogen
High blood pressure 7 (2.6) 5 (3.5) 12 (2.9) .46a
History of blood clots 2 (0.8) 0 2 (0.5) .54a
Migraines with auras 32 (12.0) 15 (10.4) 47 (11.5) .62
Current smoker and age >35 y 1 (0.4) 1 (0.7) 2 (0.5) >.99
Multiple risk factors for atherosclerotic cardiovascular diseaseb 2 (0.8) 4 (2.8) 6 (1.5) .19a
Women with a potential contraindicationc 40 (15.0) 20 (13.9) 60 (14.6) .75
Among women with a potential contraindication (n = 60)c
Prescribed a method containing estrogen 32 (80.0) 14 (70.0) 43 (71.7) .52a
Prescribed a progestin-only method 8 (20.0) 6 (30.0) 14 (23.3)
a

P value based on Fisher method on 2 × 2 cross tabulation (Fisher exact test).

b

Defined as being of age ≥40 y and either being a current smoker or having high blood pressure.

c

Defined as having high blood pressure, a history of blood clots, or migraines with auras; being a current smoker >35 y of age; or having multiple risk factors for atherosclerotic cardiovascular disease.