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. 2020 Feb 26;5(5):1–9. doi: 10.1001/jamacardio.2020.0013

Table. Distribution of Lipid Results for Internal and External Databases.

Database Range Mean (SD) Median (25th-75th Percentile) Skewness Kurtosis
NIH (N = 18 715)
HDL-C, mg/dL 5-102 40.8 (15.7) 39 (30-50) 0.6 0.6
TC, mg/dL 78-759 246.8 (87.9) 232 (186-288) 1.4 3.2
TG, mg/dL 38-3162 273.8 (392.9) 149 (98-253) 3.9 17.9
Non–HDL-C, mg/dL 53-734 206 (89.8) 190 (144-248) 1.4 3.4
BQ LDL-C, mg/dL 10-707 158.6 (83.0) 143 (103-199) 1.5 4.4
Mayo Clinic (N = 27 646)
HDL-C, mg/dL 1-201 46.3 (15.0) 44 (36-54) 1.0 3.0
TC, mg/dL 45-1830 193.6 (58.1) 188 (157-223) 3.3 57.0
TG, mg/dL 26-2690 164.7 (140.0) 127 (87-195) 5.1 50.8
Non–HDL-C, mg/dL 22-1810 147.2 (56.4) 140 (111-175) 3.8 68.5
BQ LDL-C, mg/dL 9-1775 117.7 (47.1) 112 (88-141) 5.1 118.1
Pacific Biomarker (N = 1245)
HDL-C, mg/dL 24-169 70.0 (27.7) 64 (47-89) 0.6 -0.3
TC, mg/dL 87-329 173.1 (35.4) 170 (150-194) 0.5 0.6
TG, mg/dL 27-785 113.6 (67.5) 98 (70-135) 2.8 14.9
Non–HDL-C, mg/dL 35-292 103.1 (36.3) 99 (77-123) 1.0 1.8
BQ LDL-C, mg/dL 21-222 87.0 (31.4) 84 (64-106) 0.7 0.6
Prism Health Dx Inc (N = 21 206)
HDL-C, mg/dL 10-190 53.3 (15.9) 51 (42-62) 1.0 2.1
TC, mg/dL 56-1134 188.7 (47.8) 185 (157-215) 1.7 17.1
TG, mg/dL 22-2779 152.9 (144.8) 114 (79-171) 5.5 54.3
Non–HDL-C, mg/dL 3-1100 135.4 (46.8) 130 (103-160) 2.0 20.5
Beckman dLDL-C, mg/dL 10-1214 113.3 (39.4) 110 (86-136) 2.4 46.3
LabCorp (N = 231 682)
HDL-C, mg/dL 5-180 51 (15.8) 48 (40-60) 1.0 1.8
TC, mg/dL 47-890 184 (44.6) 180 (152-210) 0.8 2.7
TG, mg/dL 16-2797 171 (156.3) 127 (88-194) 4.9 43.1
Non–HDL-C, mg/dL 11-874 133 (44.0) 128 (101-157) 1.1 3.8
Roche dLDL-C, mg/dL 3-618 109 (37.4) 106 (82-132) 0.7 1.6

Abbreviations: BQ, β-quantification; dLDL-C, direct low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; LabCorp, Laboratory Corporation of America Holdings; LDL-C, low-density lipoprotein cholesterol; NIH, National Institutes of Health; TC, total cholesterol; TGs, triglycerides.

SI conversion factors: To convert total cholesterol, HDL-C, non–HDL-C, LDL-C, and dLDL-C to millimoles per liter, multiply by 0.0259; and TGs to millimoles per liter, multiply by 0.0113.