Table 1.
Sulfation methods for alg hydroxyl groups derivatization. TBA: tetrabutylammonium.
| Starting Polymer | Sulfation Agent | Application | Ref. |
|---|---|---|---|
| Na-alg | ClSO3H/formamide | Anticoagulant heparin analogue | [43] |
| Poly-G-alg | ClSO3H/formamide | Anticoagulant heparin analogue and anti-inflammatory compound | [44] |
| TBA-alg | DCC, H2SO4/DMF | Heparin-binding proteins release | [50] |
| Na-alg | N(SO3Na)3/H2O | Anticoagulant heparin analogue | [49] |
| Na-alg, various G:M ratios | ClSO3H/formamide | Evaluation of heparin-like properties of sulfated-alg | [45] |
| TBA-alg | SO3/pyridine | Chondrocyte encapsulation | [51] |
| Na-alg | ClSO3H/formamide | Chondrocyte encapsulation | [46] |
| Na-alg | ClSO3H/formamide | Nanofiber electrospinning | [47] |
| Alginic acid, Poly-M-alg and Poly-G-alg | ClSO3H/formamide | Structure-activity relationship of propylene glycol alginate sodium sulfate (PSS) derivatives | [48] |