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. 2020 May 11;2020:9159315. doi: 10.1155/2020/9159315

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Copyright © 2020 Bo-Da Wu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Differences in the time to onset of first reported gastrointestinal symptoms or related surgery between patients with missense mutations and those with null mutations were compared by Kaplan-Meier analysis and the log-rank test. (a) The age of first detection of GI polyps (mean ± SD of missense group vs null group: 21.2 ± 4.5 vs 17.7 ± 8.6, P = 0.04). (b) The age of first occurrence of intestinal obstruction (mean ± SD18.5 ± 5.1 vs 17.8 ± 6.2, P = 0.036). (c) The age of first surgery (mean ± SD21.00 ± 7.106 vs 16.36 ± 5.956, P = 0.049).