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. Author manuscript; available in PMC: 2020 Oct 24.
Published in final edited form as: J Med Chem. 2019 Oct 4;62(20):9026–9044. doi: 10.1021/acs.jmedchem.9b00294

Figure 7: Gallinamide A (1) potently eliminates T. cruzi from murine host cells.

Figure 7:

A. Representative images of gallinamide A inhibition of T. cruzi infection. The nuclear stain allows visualization of the host and parasite nuclei in the presence of DMSO vehicle or 20 nM gallinamide A; the latter treatment eliminates the majority of parasites in infected murine cells. B. The dose response curve to intracellular parasite with IC50 = 14.7 nM ± 2.3.