Table 3:
MDADI Scores by late LCNP Status (N=889)
| Mean ± SD (95%CI) | Analysis Coefficient (95%CI) | |||||
|---|---|---|---|---|---|---|
| MDADI SCORESa | Patients with LCNP (n=36) | Patients without LCNP (n=853) | P value | Univariate (95%CI) | Multivariate (95%CI) | P value |
| Composite | 68.0 ± 17.4 (62.1 to 73.9) | 80.2 ±16.3 (79.1 to 81.3) | < 0.001 | −12.2 (−17.6 to −6.7) | −6.7 (−12.0 to −1.3) | 0.015 |
| Global | 65.1 ± 28.9 (55.3 to 74.8) | 81.3 ± 23.2 (79.8 to 82.9) | < 0.001 | −16.3 (−24.1 to −8.4) | −9.1 (−17.0 to −1.3) | 0.023 |
| Emotional | 70.1±19.2 (63.6 to 76.5) | 81.0±16.4 (79.9 to 82.1) | < 0.001 | −10.9 (−16.5 to −5.4) | −5.9 (−11.4 to −0.3) | 0.038 |
| Physical | 62.5±18.0 (56.4 to 68.6) | 75.9±19.0 (74.6 to 77.2) | < 0.001 | −13.5 (−19.8 to −7.1) | −7.7 (−14.0 to −1.3) | 0.018 |
| Functional | 74.4±20.7 (67.4 to 81.4) | 86.0±16.1 (84.9 to 87.1) | < 0.001 | −11.6 (−17.1 to −6.1) | −6.0 (−11.4 to −0.6) | 0.028 |
Abbreviations: MDADI, MD Anderson Dysphagia Inventory (MDADI); LCNP, lower cranial neuropathy. Multiple linear regression models adjusted covariates including, age, survival time, sex, education, subsite, T-stage, smoking, therapeutic modality, RT modality, solid food diet prior to treatment, and stricture. The regression model for global scores adjusted for an additional variable, neck dissection.
a
Missing values imputed.