TABLE 1.
Comparison of the top 10 genes in EBVaGC with EBVnGC in our study and EBVaGC dataset in TCGA
| EBVaGC | EBVnGC | EBVaGC in TCGA | ||||
|---|---|---|---|---|---|---|
| Gene | Number of case | Percentage | Number of case | Percentage | P‐value | Percentage |
| ARID1A | 51 | 69.90% | 15 | 20.00% | 2.92 × 10−9 | 53.85% |
| PIK3CA | 51 | 69.90% | 5 | 6.70% | 8.76 × 10−15 | 69.23% |
| LRP1B | 21 | 28.80% | 23 | 30.70% | .94 | 19.23% |
| SMAD4 | 17 | 23.30% | 2 | 2.70% | 4.59 × 10−4 | 11.54% |
| TP53 | 11 | 15.10% | 47 | 62.70% | 8.32 × 10−9 | 0 |
| KMT2D | 9 | 12.30% | 10 | 13.30% | 1 | 19.23% |
| SMARCA4 | 8 | 11.00% | 8 | 10.70% | 1 | 0 |
| BCOR | 8 | 11.00% | 2 | 2.70% | .09 | 19.23% |
| PIK3R1 | 8 | 11.00% | 1 | 1.30% | .04 | 0 |
| FAT3 | 6 | 8.20% | 19 | 25.30% | .01 | 15.38% |
Abbreviations: EBVaGC, Epstein‐Barr virus‐associated gastric cancer; EBVnGC, Epstein‐Barr virus‐negative gastric cancer; TCGA, The Cancer Genome Atlas.