FIGURE 2.

The expression of CWF19L1 is associated with the grade of glioma and confers a better prognosis for patients with glioma. A, The expression levels of CWF19L1 in the TCGA and CGGA RNAseq data sets were negatively associated with the glioma World Health Organization (WHO) grades. B, The Kaplan‐Meier curve shows the high expression of CWF19L1, suggesting that patients have a better prognosis. C, The positive correlation of CWF19L1 in CGGA patients suggests a higher correlation with the transcriptional process. D, The Cox proportional hazards regression analysis of CWF19L1 expression and other characteristics in relation to overall survival in GBM from the CGGA cohort. E, The UCSC website predicts that the CWF19L1 promoter region is rich in H3K27ac. F, ChIP‐qPCR showed the enrichment of H3K27ac in the CWF19L1 promoter region. Interestingly, H3K27me3 showed the opposite phenomenon. H, The GO analysis of HOTAIR positive correlation genes through the TCGA database