Table 1.
Morphometric parameters identified in adult, ageing and ageing Walker 256 tumour-bearing rats.
| Morphometric Parameters |
A | S | Wi | Wa | ||||
|---|---|---|---|---|---|---|---|---|
| Mean ± SD (Absolute) |
Mean ± SD (Relative) |
Mean ± SD (Absolute) |
Mean ± SD (Relative) |
Mean ± SD (Absolute) |
Mean ± SD (Relative) |
Mean ± SD (Absolute) |
Mean ± SD (Relative) |
|
| Initial body weight (g) |
245.100 ± 33.310 | - | 673.100 ± 71.110 | - | 642.700 ± 81.380 | - | 598.900 ± 56.990 | - |
| Final body weight (g) |
314.100 ± 24.250 | - | 705.000 ± 71.110 | - | 624.200 ± 93.180 | - | 570.900 ± 100.400 | - |
| Delta body weight (g) |
75.000 ± 16.800 | - | 31.700 ± 12.100 | - | −31.200 ± 31.020 | - | −51.500 ± 74.550 b | - |
| Gastrocnemius muscle weight (g) |
2.194 ± 0.189 | 0.009 ± 0.001 | 2.780 ± 0.565 | 0.004 ± 0.001 a | 2.729 ± 0.900 | 0.004 ± 0.001 | 2.638 ± 0.884 | 0.004 ± 0.001 |
| Liver weight (g) |
9.442 ± 1.214 | 0.038 ± 0.003 | 18.770 ± 2.434 | 0.027 ± 0.004 | 15.710 ± 3.482 | 0.024 ± 0.005 | 15.080 ± 4.538 | 0.025 ± 0.007 |
| Tumour weight (g) |
- | - | - | - | 12.600 ± 5.825 | 0.020 ± 0.010 | 23.560 ± 9.083 | 0.040 ± 0.017 c |
Legend: (A) control adult rat; (S) control ageing rat; (Wi) ageing tumour-bearing rat in intermediated stage; (Wa) ageing tumour-bearing rat in advanced stage. Delta body weight was calculated as [final body weight − initial body weight] for non-tumour-bearing groups and as [(final body weight − tumour weight) − initial body weight] for tumour-bearing groups. The relative values were calculated dividing gastrocnemius muscle, liver and tumour weights by the respective initial body weight of each animal. The results were presented as mean ± standard deviation (SD). Data were analysed by one-way ANOVA, followed by Tukey’s honestly significant difference (HSD) (comparison among A, S, Wi and Wa) and by t-test (comparison to Wa versus Wi). (a) P-value <0.05 in comparison to A group; (b) P-value <0.05 in comparison to S group and (c) P-value < 0.05 in comparison to Wi group.