Table A1.
Abbreviations of metabolites and their explanation used in this work.
| Abbreviation | Explanation |
|---|---|
| AAA | aromatic amino acid |
| Tyr | tyrosine |
| Trp | tryptophan |
| Phe | phenylalanine |
| APPs | acute-phase proteins |
| PAH | phenylalanine hydroxylase |
| TDO | tryptophan 2,3-dioxygenase |
| Glu | glutamic acid |
| Gly | glycine |
| Asp | aspartic acid |
| Ala | alanine |
| Lys | lysine |
| PTMs | posttranslational modifications |
| GDH | glutamate dehydrogenase |
| CPS | carbamoyl phosphate synthetase |
| AST | aspartate aminotransferase |
| OTC | ornithine transcarbamylase |
| TPH2 | tryptophan hydroxylase 2 |
| TNF-α | tumor necrosis factor-α |
| Ack | acetyl-lysine |
| Pig-MAP | pig-major acute phase protein |
| CRP | C-reactive protein |
| HP | haptoglobin |
| IL-6 | interleukin 6 |
| Kyn | kynurenine |
| SAA | serum amyloid A |
| 5-HT | 5-hydroxytryptamine |
| HPPA | 4-hydroxyphenylpyruvate |
| HGA | homogentisic acid |
| PWSD | postweaning stress syndrome |
| FDR | false discovery rate |
| TSA | trichostatin A |
| NAM | nicotinamide |
| KEGG | Kyoto Encyclopedia of Genes and Genomes |
| ANOVA | analysis of variance |
| LC-MS/MS | liquid chromatography tandem mass spectrometry |
| WT | wild-type |
| TCA | tricarboxylic acid |
| SIRT1 | sirtuin 1 |
| HPLC | high-performance liquid chromatography |
| NSI | NanoSpray Ionization |
| NCE | normalized collision energy |
| AGC | automatic gain control |
| DMEM | dulbecco’s modified eagle medium |
| PBS | phosphate buffer saline |
| SIM | selected ion monitoring |