Figure 1.

Significant associations were found between whole blood and platelet metabolites. In sepsis patients, (a) several whole blood metabolites (creatinine, glutamate, glycine, ornithine, phenylalanine) were significantly and positively correlated with at least 12/19 (63%) of the detected platelet metabolites; these are contained within the red box. These significant correlations were not present in the (b) control subjects. p-values of ≤0.05 were considered significant. Matrices were generated in RStudio using Pearson’s correlation coefficient (r) with a scale of −1 to 1.