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. 2020 May 20;21:315. doi: 10.1186/s12891-020-03328-9

Table 1.

Comparison of preoperative variables between the two groups

Transfusion(n = 391) Non-transfusion(n = 5011) t/z/χ2 P
Age, years 67 (61,72) 66 (61,71) 1.656 0.098
Sex 17.307 0.000
 Male 57 1192
 Female 334 3819
BMI, Kg/m2 26.04 (23.52,29.14) 27.34 (24.88,29.69) 5.292 0.000
Duration of disease, years 11.731 0.008
 <1 19 251
 1–3 29 562
 3–10 125 1816
 >10 218 2382
Smoking 28 503 3.387 0.066
Alcohol 24 553 9.119 0.003
Allergies 65 754 0.701 0.402
Transfusion history 58 294 47.872 0.000
Blood type (Rh) 0.000 1.000
 Rh+ 389 4990
 Rh- 2 21
Blood type (ABO) 3.748 0.290
 A 101 1493
 B 121 1540
 O 124 1401
 AB 45 577
 CCI 3 (2,3) 3 (2,3) 1.065 0.287
Indications 0.155*
 Osteoarthritis 372 4835
 Rheumatoid arthritis 16 151
 Traumatic arthritis 3 10
 Psoriatic arthritis 0 6
 Others 0 9
Procedures 653.561 0.000
 Bilateral TKA 231 570
 Unilateral TKA 160 4441
TXA use 130 2060 9.345 0.002
Comorbidities
 Hypertension 186 2549 1.578 0.209
 Diabetes mellitus 68 801 0.532 0.466
 Coronary heart disease 67 687 3.544 0.060
 Arrhythmia 9 139 0.303 0.582
 Heart failure 1 6 0.471*
 Other cardiac diseases 8 78 0.555 0.456
 Peripheral vascular disease 8 114 0.086 0.769
 Cerebrovascular disease 38 342 4.644 0.031
 Mental illness 3 45 0.070 0,791
 Pulmonary disease 9 180 1.789 0.181
 Digestive system disease 22 359 1.308 0.253
 Urinary system diseases 5 121 2.054 0.152
 Gynecologic diseases 12 149 0.011 0.915
Laboratory tests
 RET, 109/μl 61 (57,78) 64 (52,78) 3.517 0.000
 MCV, fL 89.5 (86.4,92.6) 89.4 (86.7,92.2) 0.257 0.797
 MCH, Pg 29.7 (28.6,30.7) 29.9 (28.9,30.9) 2.291 0.022
 MCHC, g/L 332.0 (324.0,340.0) 333.0 (327.0,341.0) 3.563 0.000
 Hb, g/L 80.0 (74.0,91.0) 105.0 (95.00,115.0) 23.463 0.000
 RDW, % 13.0 (12.5,13.7) 12.8 (12.4,13.3) 23.046 0.000
 PLT, 109/L 146.0 (121.0,179.0) 179.0 (149.0,213.0) 11.825 0.000
 PDW, fL 11.7 (10.8,13.2) 11.8 (10.8,13.0) 0.452 0.651

TKA Total knee arthroplasty, BMI Body mass index, CCI Charlson comorbidity index, TXA Tranexamic acid, RET Reticulocyte, MCV Mean corpuscular volume, MCH Mean corpuscular hemoglobin, MCHC Mean corpuscular hemoglobin concentration, Hb Hemoglobin, RDW Red blood cell distribution width, PLT Platelet, PDW Platelet distribution width

*Fisher's exact test