Table 1. AUC and Bioavailability of Intravenously (i.v.) or Orally (p.o.) Injected NMTa.
route of administration | AUC0–180min (min·μg/mL) | bioavailability (%) |
---|---|---|
i.v. (0.5 mg/kg BW) | 54.0 ± 3.6 | |
p.o. (0.5 mg/kg BW) | 51.9 ± 4.1 | 96.1 |
p.o. (5 mg/kg BW) | 315 ± 27.9 | 58.0 |
Data are presented as means ± standard errors of measurements from three mice per dosing group.