Figure 4.

Ginsenoside Rg1 reduces lipid accumulation in NAFLD models. (A, B) Ginsenoside Rg1 reduces fat deposition of the liver tissues in a dose- and time-dependent manner. Sections of liver tissues were detected by oil red O staining after ginsenoside Rg1 treatment for 4 or 8 weeks. C. Ginsenoside Rg1 reduces lipid factor accumulation of serum in a dose- and time-dependent manner. The serum concentrations of TG and total cholesterol (TC) were detected by an automated biochemistry analyzer after ginsenoside Rg1 treatment for 4 or 8 weeks. The values shown are mean ± SEM of the data from three independent experiments. ^#Significant compared with the control group alone, P < 0.05; *significant compared with the model group alone, P < 0.05; ^@significant compared with simvastatin alone, P < 0.05.