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. 2020 Mar 25;10(4):124. doi: 10.3390/metabo10040124

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Identified network after applying SmCCNet to adjusted proteomic and metabolomic data and percent emphysema. Proteins are blue nodes and metabolites are red nodes. Grey edges represent a negative correlation between the nodes. Purple edges represent a positive correlation between the nodes. Edge thickness corresponds to the relationships between the nodes based on the canonical weights. Node size corresponds with connectivity. Abbreviations: insulin-like growth factor-binding protein 2 (IGFBP-2), quinone oxidoreductase-like protein 1 (QORL1).