Figure 3.

(A-Top) UpSet plot to visualize the intersecting sets of features selected as precursor for MS² spectra acquisition using DDA, i-DDA, xcms-DDA or hmdb-DDA. (A-Bottom) Distribution of the 452, 388 and 261 features exclusively selected as precursors by xcms-DDA, i-DDA and hmdb-DDA, respectively. (B) Distribution of the median intensity values in the sample batch of the fragmented features selected using DDA, i-DDA, xcms-DDA and hmdb-DDA (color dots) and of features that were not fragmented (grey dots).