Skip to main content
. Author manuscript; available in PMC: 2021 Mar 18.
Published in final edited form as: J Am Chem Soc. 2020 Mar 9;142(11):5204–5211. doi: 10.1021/jacs.9b12770

Table 2.

Dissociation Constants (Kd) of Pu19m2-ligand complexes determined by MST experiments.

Substrate Ligand Kd (μM)
Guanine 19.5 ± 3.1
dG 3.1 ± 0.4
dGMP 59.3 ± 4.1
Pu19m2 DNA dGTP 510.6 ± 44.2
GMP 90.5 ± 9.2
GTP 222.8 ± 29.1
cGMP 59.3 ± 7.7
Acyclovir 4.2 ± 0.5