Table 3.

Primary walking outcomes with mean (95% CIs) at baseline (BSL), post-training (POST) and follow-up (F/U) and between-group and severity interactions p-values.

	High-intensity variable	High-intensity forward	Low-intensity variable	group × time interaction	group × severity × time interaction
Self-selected velocity (m/s)
BSL	0.52 (0.41-0.63)	0.50 (0.39-0.61)	0.50 (0.40-0.59)	<0.001 HV, HF > LV	0.21
ΔPOST	0.16 (0.10-0.21)	0.17 (0.11-0.24)	0.02 (0.00-0.05)
ΔF/U	0.16 (0.11-0.20)	0.19 (0.11-0.26)	0.04 (0.01-0.07)
Single limb stance-SSV (% gait cycle)
BSL	21 (19-24)	22 (19-24)	22 (19-25)	<0.001 HV, HF > LV	<0.001 HV/HF-severe> others
ΔPOST	2.1 (0.7-3.4)	3.5 (1.9-5.0)	0.5 (−0.4-1.4)
ΔF/U	2.6 (0.9-4.3)	3.8 (2.0-5.5)	0.9 (−0.4-1.6)
Step length asymmetry-SSV (%)
BSL	72 (60-83)	76 (68-83)	69 (60-78)	0.95	0.45
ΔPOST	4.9 (−1.1-11)	1.7 (−6.2-9.7)	2.4 (−5.4-10)
ΔF/U	3.9 (−4.3-12)	3.6 (−4.2-11)	3.8 (−4.3-12)
Fastest velocity (m/s)
BSL	0.70 (0.55-0.85)	0.65 (0.50-0.80)	0.65 (0.51-0.78)	<0.001 HV, HF > LV	0.43
ΔPOST	0.24 (0.17-0.31)	0.29 (0.20-0.37)	0.07 (0.03-0.11)
ΔF/U	0.20 (0.14-0.27)	0.23 (0.16-0.31)	0.07 (0.03-0.12)
Single limb stance-FV (% gait cycle)
BSL	24 (21-26)	23 (20-26)	23 (20-26)	0.005 HV, HF > LV	0.15
ΔPOST	2.5 (0.8-4.3)	4.1 (2.2-6.1)	0.9 (−0.1-1.8)
ΔF/U	2.6 (1.0-4.3)	3.6 (1.8-5.4)	0.9 (−0.3-2.0)
Step length asymmetry-FV (%)
BSL	73 (65-82)	75 (67-82)	70 (61-80)	0.65	0.99
ΔPOST	7.4 (2.9-12)	4.6 (−2.1-11)	3.7 (−4/1-12)
ΔF/U	6.1 (1.3-11)	4.7 (−1.2-11)	0.5 (−6.0-6.9)
Six min walk test –fastest speed (m)
BSL	212 (160-264)	197 (149-244)	197 (149-246)	<0.001 HV, HF > LV	0.96
ΔPOST	82 (61-104)	96 (69-123)	34 (21-48)
ΔF/U	77 (53-101)	76 (46-105)	38 (23-53)