Table 3.

Optimized dosage schemes ranked from the milder to the more aggressive depending on patients’ characteristics (age, weight) and needs (severity of disease).

Dosing scheme	COVID severity	Patientsa, b
Start early: 250 mg x2 for all days (or increase after Day3 depending on the disease progress)	Mild	Adults / Elder
Day1: 500 mg x2 Day 2 and afterwards: 250 mg x2	Mild / Moderate	Adults / Elder
Day 1: 500 mg x2 Day 2: 500 mg x2 Day 3 and afterwards: 250 mg x2	Moderate	Adults / Elder
Day 1: 500 mg + 500 mg + 250 mg (with 8 h intervals) Day 2: 500 mg x2 Day 3: 250 mg x2	Severe	Adults
Day 1: 500 mg + 500 mg + 250 mg (with 8 h intervals) Day 2: 500 mg x2 Day 3: 500 mg x2 Day 4 and afterwards: 250 mg x3	Severe	Adults

^aPatients weighting more than 50% from the average (70 kg), require 25% higher doses.

^bPatients weighting less than 50% from the average (70 kg), require 25% lower doses.