Table 3.
Selected envelope protein epitopes.
| Epitope | Virus | % Identity | Length | MHC Class | Alignment length | Position | e-value |
|---|---|---|---|---|---|---|---|
| SLVKPSFYV | Pangolin CoV | 100 | 9 | I | 9 | 50–58 | 7.71E-08 |
| Bat CoV | 100 | I | 9 | 50–58 | 7.71E-08 | ||
| SARS-CoV-2 | 100 | I | 9 | 50–58 | 7.71E-08 | ||
| SARS-CoV | 77.8 | I | 9 | 50–58 | 2.32E-04 | ||
| Bovine CoV | 80 | I | 5 | 56–60 | 0.048 | ||
| H-Enteric CoV | 80 | I | 5 | 56–60 | 0.048 | ||
| Canine CoV | 80 | I | 5 | 56–60 | 0.048 | ||
| LTALRLCAY | SARS-CoV | 100 | 9 | I | 9 | 34–42 | 4.94E-08 |
| Pangolin CoV | 100 | I | 9 | 34–42 | 4.95E-08 | ||
| Bat CoV | 100 | I | 9 | 34–42 | 4.95E-08 | ||
| SARS-CoV-2 | 100 | I | 9 | 34–42 | 4.95E-08 | ||
| Dromedarius CoV | 85.7 | I | 7 | 34–40 | 0.002 | ||
| Camel CoV | 85.7 | I | 7 | 34–40 | 0.002 | ||
| MERS-CoV | 85.7 | I | 7 | 34–40 | 0.002 | ||
| Avian CoV | 100 | I | 4 | 15–18 | 0.09 | ||
| LVKPSFYVY | Pangolin CoV | 100 | 9 | I | 9 | 51–59 | 1.93E-08 |
| Bat CoV | 100 | I | 9 | 51–59 | 1.93E-08 | ||
| SARS-CoV-2 | 100 | I | 9 | 51–59 | 1.93E-08 | ||
| SARS-CoV | 77.8 | I | 9 | 51–59 | 5.70E-05 | ||
| Bovine CoV | 66.7 | I | 6 | 56–61 | 0.023 | ||
| H-Enteric CoV | 66.7 | I | 6 | 56–61 | 0.023 | ||
| Canine CoV | 66.7 | I | 6 | 56–61 | 0.023 | ||
| KPSFYVY SRVKNLNS |
Pangolin CoV | 100 | 15 | II | 15 | 53–67 | 2.11E-14 |
| Bat CoV | 100 | II | 15 | 53–67 | 2.11E-14 | ||
| SARS-CoV-2 | 100 | II | 15 | 53–67 | 2.11E-14 | ||
| SARS-CoV | 86.7 | II | 15 | 53–67 | 5.88E-11 | ||
| Bovine CoV | 62.5 | II | 8 | 56–63 | 0.004 | ||
| H-Enteric CoV | 62.5 | II | 8 | 56–63 | 0.004 | ||
| Canine CoV | 62.5 | II | 8 | 56–63 | 0.004 | ||
| LLVTLAIL TALRLCA |
Pangolin CoV | 100 | 15 | II | 15 | 27–41 | 2.37E-13 |
| Bat CoV | 100 | II | 15 | 27–41 | 2.37E-13 | ||
| SARS-CoV-2 | 100 | II | 15 | 27–41 | 2.37E-13 | ||
| SARS-CoV | 100 | II | 15 | 27–41 | 2.37E-13 | ||
| Dromedarius CoV | 71.5 | II | 14 | 27–40 | 1.06E-05 | ||
| Camel CoV | 71.5 | II | 14 | 27–40 | 1.06E-05 | ||
| MERS-CoV | 71.5 | II | 14 | 27–40 | 1.06E-05 | ||
| Avian CoV | 100 | II | 4 | 15–18 | 0.27 | ||
| CNIVNVS LVKPSFYV |
Pangolin CoV | 100 | 15 | II | 15 | 44–58 | 1.49E-14 |
| Bat CoV | 100 | II | 15 | 44–58 | 1.49E-14 | ||
| SARS-CoV-2 | 100 | II | 15 | 44–58 | 1.49E-14 | ||
| SARS-CoV | 86.7 | II | 15 | 44–58 | 4.17E-11 | ||
| H-Enteric CoV | 50 | II | 16 | 49–60 | 0.023 | ||
| Canine CoV | 50 | II | 16 | 49–60 | 0.023 | ||
| LIVNSVLLF LAFVVFLLV TLAILTAL RLCAY |
SARS-CoV | 100 | 31 | II | 31 | 12–42 | 7.76E-16 |
| Pangolin CoV | 100 | II | 31 | 12–42 | 8.65E-16 | ||
| Bat CoV | 100 | II | 31 | 12–42 | 8.65E-16 | ||
| SARS-CoV-2 | 100 | II | 31 | 12–42 | 8.65E-16 | ||
| Dromedarius CoV | 71.5 | II | 14 | 27–40 | 0.01 | ||
| Camel CoV | 71.5 | II | 14 | 27–40 | 0.01 | ||
| Canine CoV | 35.7 | II | 14 | 29–42 | 1.1 | ||
| Bovine CoV | 35.7 | II | 14 | 29–42 | 1.2 | ||
| H-Enteric CoV | 35.7 | II | 14 | 29–42 | 1.2 | ||
| Avian CoV | 40 | II | 10 | 20–29 | 78 |