Table 2.

Proposed Agents For Initial Ocular Surface anti-SARS-CoV-2 Intervention.

Proposed Agents For Initial Ocular Surface anti-SARS-CoV-2 Intervention
Agent	Anti- SARS-CoV-2 Effect			Ocular Surface Application (for SARS-CoV-2-unrelated disease)
	In Vivo	In Vitro	Clinical	Human	Animal
Chloroquine Phosphate	+72	-a73	±74	+75,76(0.03%)	0
OHChloroquine	+72	0	±74	0	0
Azithromycin	+77	0	±77	+78,79(1–1.5%	+80,81 (0.2–1.5%)
Zinc	+aa82s	0	0	+83(0.25% as SO4)	+84 (0.5%)

+ denotes efficacy, - denotes inefficacy, ± denotes equivocal results, 0 denotes lack of studies.

^aFor SARS-CoV.