Table 4.
Comparison table of clinical characteristics between Q703K-positive vs. -negative uAID patients.
| Q703K+ (n: 12) | Q703K- (n: 5) | P-value | |
|---|---|---|---|
| Median age at onset (years.months) | 2.9 | 3.8 | |
| Median age at diagnosis | 5.3 | 5.8 | |
| Sex ratio (M/F) | 2.3/1 | 1/4 | 0.1189 |
| Positive familial history | 2/5 | 2/2 | 1 |
| Recurrent Fever | 10 | 3 | 0.5378 |
| Pharyngitis | 1 | 1 | 0.5147 |
| Abdominal pain | 5 | 2 | 1 |
| Neurologic symptoms | 0 | 0 | 1 |
| Adenopathy | 1 | 1 | 0.5147 |
| Urticaria | 1 | 3 | 0.0525 |
| Headache | 2 | 1 | 1 |
| Myalgia | 0 | 1 | 0.2941 |
| Arthralgia | 1 | 3 | 0.0525 |
| Rash | 1 | 0 | 1 |
| Diarrhea | 0 | 0 | 1 |
| Conjunctivitis | 0 | 0 | 1 |
| Oral aphthosis | 3 | 2 | 0.6 |
| Disease Complications | 1* | 0 | 1 |
*
severe proteinuria in the context of chronic glomerulonephritis.