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. Author manuscript; available in PMC: 2020 May 21.
Published in final edited form as: ACS Infect Dis. 2019 Jun 11;5(8):1433–1445. doi: 10.1021/acsinfecdis.9b00112

Figure 5.

Figure 5.

PYR found in media after incubation with whole cells. (A) Estimated levels of PYR in R medium after 6 or 24 h in the presence of an estimated starting 106 CFU and an initial compound concentration of 50 μM. (B) Estimated levels of PYR in NR medium after 6, 24, and 48 h in the presence of an estimated starting 106 CFU and an initial compound concentration of 100 μM. (C) Estimated levels of PYR release over 24 h in R conditions by the ΔblaC strain or complemented strain or WT Mtb cells alone or in the presence of 25 μM clavulanic acid. Results are means ± SD of triplicates.