Table 4.
Clinical applications of silk scaffolds
| Applications | Type of tissue | Scaffold format |
|---|---|---|
| Tissue engineering | Bones | Sponges (both HFIP and aqueous) |
| Fibres | ||
| Cartilage | Sponges (both types) | |
| Fibres | ||
| Soft tissue | Sponges | |
| Vascular tissues | Fibres | |
| Cervical tissues | Aqueous sponges | |
| Cornea | Films | |
| Skin | Fibres | |
| Drug delivery | Drug delivery | Microspheres |
| Growth factor delivery | Microspheres | |
| Small molecules | Microspheres | |
| Implant material | Anterior cruciate ligament (ACL) | Fibres |
| Femur defects | HFIP sponges | |
| Mandibular defects | Aqueous sponges | |
| Disease modelling | Breast cancer | HFIP sponges |
| Autosomal dominant polycystic kidney disease | Aqueous sponges |