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. 2020 Apr 27;42(1):333–342. doi: 10.1080/0886022X.2020.1745236

Figure 2.

Figure 2.

Inhibition of miR-25-3p increased the autophagy in renal cells. (A) miR-25-3p expression was detected in WT and PKD mice. (B) HE staining of kidney tissues in WT group, PKD group, PKD + inhibitor group (PKD + miR-25-3p inhibitor), inhibitor + rapamycin group. N = 6. (C–G) PKD cells were divided into control, inhibitor and inhibitor-nc (miR-25-3p inhibitor-negative control) groups. miR-25-3p expression was detected by qRT-PCR. Autophagy-related protein ULK1, LC3-I, LC3-II and p62 expressions were detected by Western blot. *p < 0.05 vs WT or control. N = 3.