Table 2.

Pharmacokinetic parameters in skin (mean ± SD; n = 5).

PK parameters	SH-G	SH-MN
T1/2α (min)	163.15 ± 2.64	188.54 ± 5.16
T1/2β (min)	101.67 ± 3.17	99.48 ± 3.65
Tmax (min)	200	240
Cmax (μg mL−1)	6.82 ± 0.20	10.80 ± 0.43*
AUC0–t	1661.49 ± 7.76	2378.97 ± 58.68**
MRT0–t (min)	270.04 ± 1.32	272.84 ± 1.15

SH-G, *p < .05; **p < .01.