Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Docking scores of active compounds 9 and 10 against human thymidylate synthase protein 6QXG.
| Compound | Docking score | Amino acid residue |
|---|---|---|
| 9 | −9.09 | Cys 195, Tyr 135 and Asn 226 |
| 10 | −8.67 | Leu 221, Asn 226 and Tyr 230 |
| 5-FU | −4.22 | Phe 80, Arg 78, Thy306 and Ile307 |
