Figure 6.

Potassium gluconate delays early wound closure. (A) Schematic of experimental design. Two 8 mm full-thickness biopsies were taken from the dorsal skin of each mouse and 50 μL collagen gels with or without potassium gluconate were pipetted onto the left side wounds. The right side wounds remained untreated, and served as additional internal controls. Both wounds were sealed using Tegaderm, and (B) wound progression was followed over the course of 14 days. The area of the wound was measured and (C) quantified over time. * (p<0.05) indicates significance between experimental conditions as determined by one-way ANOVA with Holm-Sidak post hoc analysis (n=3).