Figure 7.

Potassium gluconate reduces epidermal thickness and increases skin maturity. Cryosections of the wound sites were immunostained against cytokeratin 10 (K10). (A-C) Representative images of wound sites treated with (A) vehicle (control), (B) KG-Low, and (C) KG-High. Dotted lines indicate the dermal-epidermal junction. Double arrows indicate health tissue at the boundary of a wound site. Epidermal thickness was measured as the amount of K10 positive tissue above the dotted line. Scale: 500 μm. (D) Quantification of epidermal thickness as indicated by K10 expression. * (p<0.05), ** (p<0.01), and brackets indicates significance between indicated conditions as determined by one-way ANOVA with Holm-Sidak post hoc analysis (n=3).