Table 1.
Group | Total (n) | Final (survival/n) | Survival ratio | The number and age of mice in behavioral test | |||||
---|---|---|---|---|---|---|---|---|---|
Average age | Elevated-0 maze | Average age | Shuttle box | Average age | MWM | ||||
Control | 16, M: 6, F: 10 | 6, M: 2/6, F: 4/10 | 37.5% | 22 mo. | 12 (M: 4, F: 8) | 23 mo. | 9 (M: 4, F: 5) | 23.5 mo. | 7 (M: 2, F: 5) |
Donepezil | 15, M:6, F: 9 | 6, M: 2/6, F: 4/9 | 40% | 22 mo. | 12 (M: 5, F: 7) | 23 mo. | 10 (M: 4, F: 6) | 23.5 mo. | 7 (M: 2, F: 5) |
Memantine | 15, M: 6 F:9 | 6, M: 3/6, F: 5/9 | 53.3% | 22 mo. | 13 (M: 5, F: 8) | 23 mo. | 10 (M: 4, F: 6) | 23.5 mo. | 8 (M: 3, F: 5) |
Melatonin | 15, M: 6, F: 9 | 9, M: 4/6, F: 5/9 | 60% | 22 mo. | 11 (M: 5, F: 6) | 23 mo. | 10 (M: 4, F: 6) | 23.5 mo. | 8 (M: 3, F: 5) |
LW | 15, M: 6, F: 9 | 9, M: 3/6, F: 6/9 | 60% | 22 mo. | 12 (M: 5, F: 7) | 23 mo. | 10 (M: 4, F: 6) | 23.5 mo. | 8 (M: 4, F: 4) |
M, male; F, female.