Fig 3. A high-salt high fat diet disrupted the circadian rhythm of caecal corticosterone secretion.

(A) diurnal rhythms of caecal corticosterone secretion in different groups. (B) A schematic representation of glucocorticoid synthesis pathways. (C) Relative mRNA expression levels of StAR, Cyp11a, Cyp11b1 in the adrenal gland in different groups. Black solid line: C (normal salt and control diet); grey solid line: HF (normal salt and high-fat diet); dotted line: HFS (high-fat and high-salt diet). The data represent the means ± standard error of the mean. *p<0.05 HF vs. HFS, **p<0.05 HF vs. C.