Fig 5. Cigarette smoke decreases macropinoctosis.

Primary human SAEC were exposed to either air or cigarette smoke for 60 minutes at the air-liquid interface. Following exposure cells were treated with FITC-dextran (250 μg/mL) as described in the materials and methods. (A) Representative photographs from one cell strain. All three SAEC strains showed similar results. (B) Analysis of cell fluorescence by flow cytometry for FITC-dextran uptake. Each pair of points represents an SAEC strain from a different donor. *p<0.05 by two way ANOVA with Sidak correction.