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. 2020 May 21;15(5):e0233519. doi: 10.1371/journal.pone.0233519

Table 4. Correlations between selected biochemical markers in CSF and the indicated diagnoses.

Parameters Diagnosis
MS CIS NIND OIND Control All
CHI3L1 vs. NFL rs 0.460 0.422 0.503 0.964 0.857 0.595
P 0.002 0.131 0.003 <0.001 0.0137 <0.0001
n 42 14 31 7 7 105
CHI3L1 vs. pNFH rs 0.691 -0.091 0.691 0.550 0.662 0.744
P <0.001 0.802 <0.001 0.125 0.010 <0.0001
n 35 10 43 9 14 115
CHI3L1 vs. CXCL13 rs 0.302 0.421 0.391 0.371 0.205
P 0.052 0.133 0.059 0.4131 n.a. 0.0482
n 42 14 24 7 93

MS, multiple sclerosis; CIS, clinically isolated syndrome; OIND, other central nervous system inflammatory diseases, NIND, non-inflammatory diseases of the central nervous system, IDPNS, inflammatory diseases of the peripheral nervous system; rs, Spearman’s correlation coefficient; n.a., not applicable