Table 4. Correlations between selected biochemical markers in CSF and the indicated diagnoses.
Parameters | Diagnosis | ||||||
---|---|---|---|---|---|---|---|
MS | CIS | NIND | OIND | Control | All | ||
CHI3L1 vs. NFL | rs | 0.460 | 0.422 | 0.503 | 0.964 | 0.857 | 0.595 |
P | 0.002 | 0.131 | 0.003 | <0.001 | 0.0137 | <0.0001 | |
n | 42 | 14 | 31 | 7 | 7 | 105 | |
CHI3L1 vs. pNFH | rs | 0.691 | -0.091 | 0.691 | 0.550 | 0.662 | 0.744 |
P | <0.001 | 0.802 | <0.001 | 0.125 | 0.010 | <0.0001 | |
n | 35 | 10 | 43 | 9 | 14 | 115 | |
CHI3L1 vs. CXCL13 | rs | 0.302 | 0.421 | 0.391 | 0.371 | 0.205 | |
P | 0.052 | 0.133 | 0.059 | 0.4131 | n.a. | 0.0482 | |
n | 42 | 14 | 24 | 7 | 93 |
MS, multiple sclerosis; CIS, clinically isolated syndrome; OIND, other central nervous system inflammatory diseases, NIND, non-inflammatory diseases of the central nervous system, IDPNS, inflammatory diseases of the peripheral nervous system; rs, Spearman’s correlation coefficient; n.a., not applicable