Table 5. Categorical comparison of the selected variables expressed in positivity or negativity of test with individual diagnosis using Fisher’s exact test, because we compared quantitative methods (CHI3L1, NFL, pNFH, CXCL13) with qualitative methods (oligoclonal bands IgG, IgM, FLC kappa and FLC lambda).
| Methods (n) | Fisher exact test P | Sample distribution | Diagnosis | ||||
|---|---|---|---|---|---|---|---|
| CIS | MS | IDPNS | NIND | OIND | |||
| CHI3L1 (117) | 0.0770 | Neg | 13 | 37 | 3 | 35 | 6 |
| Pos | 1 | 5 | 1 | 11 | 5 | ||
| CXCL13 (104) | 0.0004 | Neg | 8 | 32 | 4 | 28 | 4 |
| Pos | 9 | 11 | 0 | 2 | 6 | ||
| NFL (106) | 0.3775 | Neg | 13 | 25 | 2 | 19 | 4 |
| Pos | 3 | 18 | 2 | 16 | 4 | ||
| pNFH (104) | <0.0001 | Neg | 11 | 33 | 2 | 26 | 4 |
| Pos | 0 | 2 | 2 | 18 | 6 | ||
| oIgG (106) | <0.0001 | Neg | 5 | 5 | 8 | 18 | 9 |
| Pos | 11 | 38 | 0 | 6 | 6 | ||
| oIgM (55) | 0.0001 | Neg | 3 | 7 | 1 | 17 | 3 |
| Pos | 4 | 16 | 0 | 1 | 3 | ||
| oFLC Kappa (132) | <0.0001 | Neg | 2 | 6 | 3 | 46 | 6 |
| Pos | 13 | 37 | 1 | 10 | 8 | ||
| oFLC Lambda (132) | <0.0001 | Neg | 7 | 15 | 3 | 53 | 9 |
| Pos | 8 | 28 | 1 | 3 | 5 | ||