Table 4.

Correlation between differentially expressed miRNAs and estimated glomerular filtration rate, other clinical parameters, and vascular mechanical properties

Parameters	let-7g-5p			miR-191-5p			eGFR
	R 2	Type	P	R 2	Type	P	R 2	Type	P
Age	0.208	Neg	<0.001				0.275	Neg	<0.001
eGFR	0.297	Pos	<0.001	0.259	Pos	<0.001	NA	NA	NA
UACR							0.125	Neg	<0.05
Carotid distensibility	0.106	Pos	<0.05				0.083	Pos	<0.05
Carotid femoral PWV	0.099	Neg	<0.05
Neutrophil fraction	0.219	Neg	<0.05	0.187	Neg	<0.05	0.144	Neg	<0.05
Lymphocyte fraction	0.176	Pos	<0.05	0.139	Pos	<0.05	0.119	Pos	<0.05
Neutrophil number	0.268	Neg	<0.001	0.102	Neg	<0.05	0.102	Neg	<0.05
Lymphocyte number				0.086	Pos	<0.05
Neutrophils/lymphocytes	0.216	Neg	<0.05	0.193	Neg	<0.05	0.153	Neg	<0.05

The log₂ fold change of let-7g-5p and miR-191-5p expression levels determined by reverse transcription-quantitative PCR was used to determine simple linear correlations with clinical parameters and vascular mechanical properties. The square of the Pearson correlation coefficient (R²), the type of correlation (positive (Pos) or negative (Neg)), and the probability (P) are shown. n = 50 for let-7g-5p and miR-191-5p and 61–62 for estimated glomerular filtration rate (eGFR). Abbreviations: NA, non applicable; PWV, pulse wave velocity; UACR, urinary albumin/creatinine ratio.