TABLE 1.
Case | Clinical Diagnosis | Gender | FTLD-TDP Subtype | Race | Handedness | Age at Death | Brain wt (g) | Disease Duration (years) | PMI (hours) | Fixation Method |
---|---|---|---|---|---|---|---|---|---|---|
1 | PPA-G | Male | Type A | C | Right | 70 | 999 | 4 | 4 | F |
2 | PPA-L | Male | Type A | C | Left | 65 | 1040 | 8 | 6 | F |
3 | PPA-M | Female | Type A | C | Right | 74 | 1035 | 7 | 10 | F |
4 | PPA-G | Male | Type B | C | Right | 55 | 1090 | 4 | 29 | F |
5 | PPA-L → PPA-G | Male | Type B | C | Right | 59 | 1490 | 2 | 12 | F |
6 | bvFTD | Female | Type A | C | Right | 65 | 980 | 8 | unk | P |
7 | bvFTD | Female | Type B | C | Left | 59 | 810 | 8 | 23 | F |
PPA clinical subtypes: L, logopenic; G, agrammatic; M, mixed. Participant 5 progressed from logopenic to agrammatic. bvFTD, behavioral variant frontotemporal dementia. Race: C, Caucasian; PMI, postmortem interval; unk, unknown. Fixation method: F, formalin; P, 4% paraformaldehyde.