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. 2020 Apr 24;143(5):1541–1554. doi: 10.1093/brain/awaa074

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© The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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The fundamental components of post-stroke aphasia and their neural correlates. (A) Loadings of behavioural measures on language and cognitive components extracted from a varimax rotated PCA with loadings > 0.3 (note the loadings of some measures on two components). WPM = words per minute. (B) Neural correlates associated with these components identified using VBCM thresholded at P < 0.001 voxel-level and FWE cluster-level corrected at P < 0.05 with demographic variables (age, education, and time post-stroke onset) entered as covariates, except for Component 7, which included lesion volume as covariate (as the cluster associated with this component was not significant without lesion volume correction). Images are at maximum intensity projection.