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(A) Monthly unadjusted and seasonally adjusted (dashed line) dispensing counts of PPIs and statins; (B) dispensing counts of PPIs by strength: high, standard and low, from July 2012 to June 2018. NPS MedicineWise’s PPI program start and end and Choosing Wisely Australia recommendations 1 and 2 marked at April 2015 and may 2016. Standard strength PPI esomeprazole was made available over the counter in February 2016. PPIs, proton pump inhibitors
