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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Crit Care Med. 2020 Mar;48(3):353–361. doi: 10.1097/CCM.0000000000004139

Table 2:

Correlations among baseline biomarkers of Inflammation, neuro-protection, and astrocyte and glial activation

Biomarkers IGF-1 IL10 IL6 IL8 CRP S-100β TNF-alpha
IGF-1
Correlation 1.00 −0.11 −0.03 −0.18 0.08 −0.24 −0.05
P-value 0.051 0.536 0.002 0.130 <.0001 0.410
N 320 319 319 319 319 317 319
IL10
Correlation 1.00 0.43 0.46 0.04 0.27 0.40
P-value <.0001 <.0001 0.477 <.0001 <.0001
N 320 320 320 318 316 320
IL6
Correlation 1.00 0.55 0.42 0.20 0.52
P-value <.0001 <.0001 <.0001 <.0001
N 320 320 318 316 320
IL8
Correlation 1.00 0.20 0.29 0.60
P-value <.0001 <.0001 <.0001
N 320 318 316 320
CRP
Correlation 1.00 0.04 0.41
P-value 0.482 <.0001
N 319 316 318
S-100β
Correlation 1.00 0.33
P-value <.0001
N 317 316
TNF-alpha
Correlation 1.00
P-value
N 320

IL: Interleukin, IGF-1: Insulin-like growth factor-1, CRP: C-reactive protein, TNF: Tumor Necrosis Factor