Table 1.
Clinical characteristics of St Mark’s Hospital colonoscopy patients donating colonic biopsies.
| Characteristic | HC | CD | UC |
|---|---|---|---|
| n | 23 | 11 | 18 |
| Male/female | 13/10 | 4/7 | 12/6 |
| Median age [95% CI] at sampling | 51.5 [41–57] | 43 [28–57] | 53.5 [47–60] |
| Median age [95% CI] at diagnosis | 26 [18–47] | 35 [29–42] | |
| Inflammation: endoscopic subscores for UC: | |||
| Mayo 0 | 8 | ||
| Mayo 1 | 3 | ||
| Mayo 2 | 6 | ||
| Mayo 3 | 1 | ||
| IBD medications at sampling: | |||
| Aminosalicylates | 4 | 15 | |
| Azathioprine/6-mercaptopurine | 4 | 1 | |
| Buscopan | 1 | 0 | |
| Adalimumab | 1 | 0 | |
| None | 4 | 3 | |
| Non-IBD medications at sampling: | |||
| Metformin/gliclazide/statin | 0 | 2 | |
| Ondansetron | 1 | 0 | |
| Certirazine | 1 | 0 | |
| None | 9 | 16 |
Demographic and clinical data analysed in Figures 2, 4d, and Supplementary Figure S1, available as Supplementary data at ECCO-JCC online.
HC, healthy controls; CD, Crohn’s disease; UC, ulcerative colitis; CI, confidence interval.