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. 2020 Apr 14;9:e53350. doi: 10.7554/eLife.53350

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© 2020, Bates et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 5. — (a) Three FlyCircuit neurons along with mirrored versions; a visual projection neuron, OA-VUMa2 (Busch et al., 2009) and the CSD interneuron (Dacks et al., 2006). Co-visualisation facilitates the detection of differences in innervation, such as the higher density of innervation for the CSD interneuron in the lateral horn on the contralateral side compared to the ipsilateral lateral horn. (b) Neurons from the same side of the brain and alternate side of brain are compared and a similarity score generated. (c) Distributions of similarity scores for comparisons within the same brain hemisphere and across brain hemispheres. These scores are similar, because the mirroring registration is good. (d) Sequence of 12 example neurons (black) with mirrored counterparts (grey), having equally spaced similarity scores. Below, full distribution of scores for all neurons in FlyCircuit dataset. (e) Segment-by-segment measures of neuron similarity. Redder shades correspond to low degrees of symmetricity, bluer shades higher. Flipped version of neuron in gray.

Figure 5—figure supplement 1. — (a) Three FlyCircuit neurons along with mirrored versions; a visual projection neuron, OA-VUMa2 (Busch et al., 2009) and the CSD interneuron (Dacks et al., 2006). Co-visualisation facilitates the detection of differences in innervation, such as the higher density of innervation for the CSD interneuron in the lateral horn on the contralateral side compared to the ipsilateral lateral horn. (b) Neurons from the same side of the brain and alternate side of brain are compared and a similarity score generated. (c) Distributions of similarity scores for comparisons within the same brain hemisphere and across brain hemispheres. These scores are similar, because the mirroring registration is good. (d) Sequence of 12 example neurons (black) with mirrored counterparts (grey), having equally spaced similarity scores. Below, full distribution of scores for all neurons in FlyCircuit dataset. (e) Segment-by-segment measures of neuron similarity. Redder shades correspond to low degrees of symmetricity, bluer shades higher. Flipped version of neuron in gray.