Table 1.
Sociodemographic characteristics and S100B, tau, NSE, active caspase-3, M30, and M65 serum levels of the autism spectrum disorder and control groups
| Parameters | Patients (n = 43) | Controls (n = 41) | pvalue | x 2 | Z |
|---|---|---|---|---|---|
| Sex, F/Ma | 13 (30.2)/30 (69.8) | 10 (24.4)/31 (75.6) | 0.548 | 0.360 | |
| Age (yr)b | 6 (3) | 7 (3) | 0.217 | −1.235 | |
| Mother’s age (yr)b | 34 (11) | 32 (8) | 0.713 | −0.368 | |
| Father’s age (yr)b | 37 (11) | 37 (6) | 0.527 | −0.633 | |
| S100B (pg/ml)b | 49.13 (2.12) | 24.33 (32.64) | < 0.001 | −5.979 | |
| Tau (pg/ml)b | 131.4 (183.2) | 57.5 (47) | 0.002 | −5.979 | |
| NSE (ng/ml)b | 3.04 (1.15) | 2.65 (0.42) | 0.002 | −3.043 | |
| Active caspase 3 (pg/ml)b | 543.2 (403.5) | 415 (225.5) | 0.005 | −2.837 | |
| M30 (mlU/ml)b | 19.37 (8.36) | 16.22 (1.21) | < 0.001 | −4.484 | |
| M65 (ng/ml)b | 0.30 (1.55) | 0.20 (0.11) | 0.004 | −2.854 |
Values are presented as median (interquartile range).
NSE, neuron-specific enolase; S100B, serum 100 beta protein; F, female; M, male.
a
Chi-square pvalue, b Mann−Whitney U pvalue.