Fig. 3.

Effects of co-administration of Citicoline (100, 250, 500 mg/kg) and MgSO4 (50 mg/kg) on d₂ index in Object Recognition task. The d₂ index values have been shown for the studied group. The data represent as means ± standard error of mean of 7 mice per group. AlCl3 was orally administrated for 28 days. Citicoline and MgSO4 were injected intraperitoneally for 28 consecutive days. RVT, rivastigmine injected intraperitoneally for 28 days at the dose of 2 mg/kg; AlCl3, Aluminium chloride; MgSO4, Magnesium sulfate.

^a p < 0.001 vs. AlCl3-treated group. ***p < 0.001 vs. MgSO4-treated group. ^# p < 0.001 vs. control vehicle treated group. ^$ p < 0.05, ^$$$ p < 0.001 vs. respective Citicoline treated group (Tukey test).