TABLE 4.
Cross-sectional Multivariate Associations Between Prostate Cancer, ADT use and Odds of Mild of Cognitive Impairment (N=2,385)
| Variable | Odds Ratio | Low 95% CI | High 95% CI |
|---|---|---|---|
| Age (y) at first visit | 1.06 | 1.04 | 1.08 |
| Education (y) | 0.88 | 0.84 | 0.91 |
| Charlson index | 1.09 | 1.05 | 1.14 |
| BAI | 1.08 | 1.05 | 1.11 |
| BDI (>13) | 1.53 | 1.02 | 2.29 |
| Any APOE4 | 1.28 | 0.98 | 1.67 |
| Diabetes mellitus | 0.85 | 0.62 | 1.16 |
| Hypertension | 1.19 | 0.87 | 1.63 |
| Prostate cancer | 0.73 | 0.51 | 1.04 |
| ADT exposure | 0.95 | 0.20 | 4.41 |
ADT indicates androgen deprivation therapy; BAI, Beck Anxiety Index; BDI, Beck Depression Inventory.